看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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Currently available feasibility data for possible combination strategies.
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9 z+ G5 A1 M& f h' O+ lCombination Feasibility according to preliminary data - k$ B4 H. k6 {1 K
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Bevacizumab + sorafenib Yes, reduced dose
j! q( D% P# w9 q ~# VBevacizumab + sunitinib† No & W) y$ z8 S4 W8 {# z+ E
Bevacizumab + temsirolimus Yes
) A- R9 F# F L' e; t( |3 BBevacizumab + everolimus Yes / T* A& X2 P. T/ P% Y% k
Sorafenib + sunitinib ?
) D, L* V2 l/ d6 ZSorafenib + temsirolimus Yes, reduced dose
, _5 I! F# W& `# a/ Y# oSorafenib + everolimus Yes, reduced dose
; M! F0 ^% U% T7 Z- r. Y/ vSunitinib + temsirolimus† No
3 W6 l, `; @: f& R" m. v' }& lSunitinib + everolimus ?
. K r4 l* O* z" ?! TTemsirolimus + everolimus ?
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% s8 D( T( V+ @5 F( b6 b†Led to US FDA warning.+ a2 L3 \/ g0 h- {- y) Z
?: As yet unattempted combination.! u( x# ?( j7 @6 H, C% c: W0 O
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